DSG-I型肝病治疗仪合中药外敷治疗慢性乙型肝炎

目的:观察DSG-I型肝病治疗仪配合中药外敷治疗慢性乙型肝炎的临床疗效.方法:随机将60例患者分成观察与对照两组,各30例.观察组用治疗仪加外敷中药治疗,对照组单纯药物治疗,比较两组疗效.结果:相同条件下,观察组临床症状改善明显优于对照组,ALT、AST下降幅度大于对照组,两组比较.差异有显著性意义;ALT复常率,观察组53.3%,对照组25%,两组比较差异有显著性意义,P<0.01.结论:DSG-I型肝病治疗仪配合肝区中药外敷对改善患者临床症状,恢复肝功能有一定作用.     

气相色谱法测定辣椒风湿膏中薄荷脑与冰片的含量

目的建立辣椒风湿膏中薄荷脑与冰片的含量测定方法。方法采用气相色谱法,用水蒸气蒸馏法提取薄荷脑、冰片,以萘作为内标物,使用PEG20M色谱柱,用氢火焰离子检测器检测。结果通过方法学考察,薄荷脑在1.008μg～5.042μg范围内呈良好的线性关系,平均回收率为95.9%(n=5)。冰片在1.008μg～5.040μg范围内呈良好的线性关系,平均回收率为96.0%(n=5)。结论方法简便、准确、重现性好、精密度高。可用于控制辣椒风湿膏的质量。     

痛泻宁穴位敷贴治疗溃疡性结肠炎的实验研究

目的:探讨痛泻宁贴膏剂治疗溃疡性结肠炎的作用机理及安全性。方法:分别选用小鼠、大鼠、家兔等实验动物对痛泻宁贴膏剂进行抗炎实验、镇痛实验、经口急毒实验、皮肤刺激实验等研究。结果:痛泻宁贴膏剂有明显抑制小鼠耳廓肿胀、抑制疼痛的作用,经口急性毒性的LD50>5 000mg/kg,贴膏剂对正常及损伤皮肤均无刺激。结论:痛泻宁贴膏剂有明显的抗炎及抑制疼痛的作用,安全无毒,对皮肤无刺激性。     

针刺配合耳穴贴压治疗失眠症的疗效观察

目的　观察针刺配合耳穴贴压治疗失眠症的疗效。方法　把失眠患者随机分成 3组 ,综合组采用针刺配合耳穴贴压 ,与单纯针刺及耳穴贴压比较。结果　 3组均能有效治疗失眠症 ,总有效率分别为 95 .5 6%、 84.3 8%和 77.14 % ,但综合组愈显率为 71.11% ,针刺组及耳穴组愈显率为 40 .63 %和 3 1.43 % ,差异有显著性意义 (P<0 .0 5 ) ,且综合组的疗程短于针刺组及耳穴组 ,差异有显著性意义 (P<0 .0 5 )。结论　针刺配合耳穴贴压治疗失眠症有较好的疗效     

腹水膏穴位贴敷对小鼠艾氏腹水癌的疗效影响

观察腹水膏穴位贴敷对小鼠艾氏腹水癌的疗效 ,并从细胞因子角度探讨其治疗机理。采用艾氏腹水癌瘤株用NIH小鼠接种 ,随机分正常空白对照组 (正空组 )、模型对照组 (模对组 )、局部贴敷组 (局贴组 )、穴位贴敷组 (穴贴组 ) 4组进行观察研究。结果 ,与模对组相比 ,腹水膏局贴或穴贴均可显著延长荷瘤小鼠生存期 (P <0 0 5 ,P <0 0 1) ,显著抑制恶性腹水增长速度 (P <0 0 5 ,P <0 0 1) ,穴位贴敷优于局部贴敷 (P <0 0 5 ) ;腹水膏可下调外周血sIL 2R水平 (P <0 0 5 ) ,显著提高外周血TNF杀伤活性 (P <0 0 0 1)。艾氏腹水癌小鼠存在细胞因子网络的调节失衡 ,腹水膏治疗艾氏腹水癌疗效确切 ,其机理可能为下调外周血sIL 2R水平 ,提高外周血TNF杀伤活性 ,促进细胞免疫功能。     

无痛肠镜单人操作132例临床分析

[目的]探讨无痛结肠镜单人操作方法。[方法]采用丙泊酚注射液静脉麻醉,行无痛结肠镜单人操作单人操作技术。[结果]132例肠镜检查中,有127例插至回盲部,21例进入末段回肠,所有病例均无穿孔、出血等并发症发生,插至回盲部成功率96.21%。[结论]在麻醉睡眠情况下进行结肠镜单人操作,受检病人始终处于放松状态,易于接受,并省时省力,值得临床进一步推广。     

中药内外结合治疗甲亢疗效观察

目的：观察中药内外结合治疗甲亢的临床疗效。方法：将60例患者随机分为中药内外合治组（简称治疗组）和西药对照组（简称对照组）,每组30例。治疗组内服甲亢方,同时用甲亢平膏外敷甲状腺,每日1次,每次使用不超过10h;对照组口服丙基硫氧嘧啶,每日用量300～600mg,分3～4次服用,根据病情可逐渐递减药量。两组患者均治疗4w为1个疗程,观察2个疗程。结果：两组证候疗效比较,治疗组痊愈率（10.0%）及显效率（76.6%）均优于对照组,两组间有极显著性差异（P〈0.01）;在改善临床症状上治疗组优于对照组（P〈0.05或P〈0.01）。总有效率比较,两组间无显著性差异（P〉0.05）。结论：中药内外合治治疗甲亢是一条行之有效的治疗方法,值得进一步推广应用。     

Identification and quantification of anthocyanin pigments in colored rice

Anthocyanin pigments from varieties of black, red and wild rice were identified and quantified to evaluate their potential as nutritional function, natural colorants or functional food ingredients. Anthocyanin extraction was conducted with acidified methanol with 0.1M HCl (85:15, v/v) and identification of anthocyanin, aglycone and sugar moieties was conducted by comparison with purified standards by HPLC, Ultraviolet-Visible absorption spectrophotometer and paper chromatography. Black and wild rice showed three different types of pigments by HPLC whereas red rice variety did not show any anthocyanins. Out of three pigments detected, one (peak 2) was characterized as cyanidin-3-glucoside (C3G) by comparison of spectroscopic and chromatographic properties with an authentic standard, and another (peak 3) was tentatively identified as cyanidin-fructoside on the basis of spectroscopic properties with λ_max of aglycone in 1% HCl methanol at 537 nm, electrospray ionization mass spectra with major ions at 449 and 287 m/z and chromatographic properties. But another pigment (peak 1) has not been characterized. The most abundant anthocyanin in black and wild rice was C3G.     

Normal haematology of the white-bellied (Eupodotis senegalensis), little black (Eupodotis afra) and Heuglin's (Neotis heuglinii) bustards

Blood samples were collected from three white-bellied (Eupodotis senegalensis), four little black (Eupodotis afra) and five Heuglin's (Neotis heuglinii) bustards. All birds were captive adults and clinically normal at the time of sampling. Standard haematology assays were carried out to establish normal reference values for the three species. The results obtained are compared with similar studies conducted in the houbara (Chlamydotis undulata macqueenii), rufous-crested (Eupodotis ruficrista) and kori (Ardeotis kori) bustards.     

Properdin factor B in black Type 1 (insulin-dependent) diabetic patients

Summary The properdin factor B(Bf) variant F1 was found in 20% of 70 black patients with Type 1 (insulindependent) diabetes compared with 7.3% of 165 control subjects, yielding a significant relative risk of 3.1. In addition, the BfF allele was negatively associated with Type 1 diabetes among blacks, resulting in a relative risk of 0.4. The data suggest that Type 1 diabetes in black Americans may be partially due to admixture of Caucasoid genes.